GeaNUS Technology

Pharma Science & Tech ’24 Workshop 2 : Hands-on Workshop on Tablets and Tableting

Tablets and Tableting Workshop Information

Date: 5-8 June 2024
Workshop Venue: Level 2, Block C3, Maple Science Park, Qixia District, Nanjing, China
Course Conductors: Dr Metin Celik & Dr Paul Heng

Objectives

This comprehensive 4-day hands-on workshop will provide you the opportunity to explore the latest advancements and techniques in tablet formulation and manufacturing. Lectures accompanied by hands-on practical will help you to design tablet formulations based on SUPAC guidelines and the QbD approach, and master risk assessment and design space development.

Understand the physics of compaction, prepare tableting feeds through granulation, and gain hands-on experience in tablet making, particularly for continuous tablet production. Discover the nuances of granule preparation by various methods and their impact on tableting and the choice of excipients. You will learn to interpret compaction data from instrumented tablet presses and gain knowledge on the compaction cycle and the importance of dwell time. Lectures include exploring the fundamentals of tableting equipment and tackling common tableting problems with effective solutions. The use and development of Artificial Intelligence techniques for pharmaceutical applications will be discussed. Don’t miss this opportunity to enhance your knowledge and skills in tablet formulation and manufacturing.

Lectures

  • Tablet formulation design based on SUPAC guidelines and QbD approach
  • Risk assessment and design space development
  • Theory and practice of pharmaceutical compaction I: Physics of compaction
  • Theory and practice of pharmaceutical compaction II: Practice
  • Preparation of tabletting feeds by granulation
  • How to make use of compaction data obtained from instrumented tablet press
  • The compaction cycle and importance of dwell time
  • Characterization, functionality, and selection of tableting excipients
  • Fundamentals of tableting equipment
    • Feed material requirements for tablet formulation
    • Managing tablet press effectiveness
  • Common tableting problems: Causes and solutions
  • Characterization of tablets
  • Use of AI [expert systems] in pharmaceutical applications

Hands-on Practice

  • Introduction to granulation by high shear, fluid bed and roller compaction
  • Understanding compaction profile with simulator
  • Comparison of tableting feeds; direct compression vs granulated feeds
  • Determination of tabletability & understanding compaction tools
  • Preparation & evaluation of granules and tablets

Note

  • Course materials will be supplied.
  • Daily lunches and teas will be provided.
  • Limited class size: Registration subjected to availability & on a first-come-first-served basis.